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Karampetsou M, Vekrellis K, Melachroinou K (2022) The promise of the TGF- superfamily as a therapeutic target for Parkinsons disease

Coombes, M

Following maximally stimulated cortisol output in healthy subjects and those with adrenal adenoma, plasma concentrations of apoB, but not HDL-C or HDL- and LDL-particle concentrations, were lower in samples obtained from the adrenal veins compared with the inferior vena cava.(7) In contrast to absent or near absent levels of circulating LDL-C observed in those with hypobetalipoproteinemia, individuals with familial hypercholesterolemia (FH), characterized by high circulating levels of LDL-C secondary to well defined genetic mutations (LDLR, APOB, and PSCK9) which limit adrenal uptake of LDL-derived cholesterol, exhibit normal adrenal function

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