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The mechanism may be related to curculigoside significantly reducing AD-promoting factors (e.g., A1-42, p-tau) and increasing ferroptosis protective factors (e.g., GPX4, SLC7A11, GSH) in the hippocampus and cortex of AD mice, 574 suggesting that the natural compound curculigoside can be used as a promising therapeutic agent to improve AD by inhibiting ferroptosis

Liquid formulations taken orally are also absorbed well, but I dont recommend them for patients who test positive for parietal cell antibodies or those with severe B12 deficiencies

Minimize the Risk of Depression Several studies have identified a correlation between low vitamin B12 levels and depression