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doi: 10.1038/ncomms11463 205 de KlerkEHebrokM

Metab Brain Dis 36(7):19571968

In summary, while the existing evidence points toward a beneficial role for GA in liver disease, the consistent positivity should be interpreted with caution, likely reflecting a combination of genuine therapeutic activity, methodological limitations, and publication bias

In another study, rats with diabetic kidney disease (DKD) were treated with a CD38 inhibitor, resulting in increased renal NAD + levels, which in turn decreased mitochondrial oxidative stress 144