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Additionally, research has illuminated potential mechanisms involved in TGF-1-induced ASM remodeling, encompassing pathways such as the phosphorylation of p38 and ERK1/2 (284), the up-regulation of miR-181a and miR-328-3p through the suppression of phosphatase and tensin homolog (PTEN) protein and increased p-Akt/Akt ratio suggesting TGF-1 induced ASM remodeling involves PTEN and Akt signaling pathway (285, 286), and the modulation of intracellular calcium levels [(Ca2+)i] and/or activation of Rho-associated protein kinase (ROCK) (287)

Characterization of CaT, CaT-ME and GHK-cu/cat-me 1 H NMR spectra of CaT samples dissolved in CDCl 3 were recorded with a Bruker Avance spectrometer at 400 MHz

Thymol, a monoterpenoid phenol, suppresses the expression of genes involved in the tricarboxylic acid (TCA) cycle, resulting in diminished energy production and inhibited growth of Fusarium species (Zhang et al., 2018)