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Topical calcipotriol plus oral fumaric acid is more effective and faster acting than oral fumaric acid monotherapy in the treatment of severe chronic plaque psoriasis vulgaris

Interestingly, iron ions serve as cofactors for PHD enzymes, which hydroxylate and target HIF-1 for degradation (Lawson et al., 2024

In parallel, iron-handling disturbances (such as labile iron accumulation and ferritinophagy-mediated iron release) initiate a pre-ferroptotic state, lowering the threshold for ferroptotic execution upon inflammatory or mechanical insults (13,14)

We found that Daphnia treatment with Roundup led to an increase in CP content as compared with the control group (Figure 2C(Fig