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Phase-3 : The toxins get removed from the body mainly by the kidneys (urine) and liver (bile)

Interaction with other non-enzymatic antioxidants While GSH is the most important small molecular weight antioxidant produced in the cells, there are other small molecular antioxidants obtained from the diet such as vitamins E (-tocopherol) and C (ascorbic acid)

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Experimental results demonstrated that apelin-13, an endogenous ligand of the G protein-coupled receptor angiotensin II protein J (APJ), increased DRP1 expression, inhibited fusion-related protein expression, and stimulated VSMC mitophagy and abnormal proliferation, which exacerbated the development of atherosclerosis [227]