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Tirzepatide is administered as a once-weekly subcutaneous injection, with dosing typically initiated at 2.5 mg and increased by 2.5 mg every 4 weeks up to a maintenance dose of 5-15 mg based on tolerability and therapeutic response

For initial vaccination, the BioNTech/Pfizer, Moderna, Novavax, and AstraZeneca/ Oxford vaccines are given via injection in two doses at specific intervals (see Table 1 for more information)

For signicant deciencies, injections might be administered more frequently at the start (e.g., weekly), and once levels stabilize, the frequency can be reduced (e.g., monthly)