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2 Ferroptosis: molecular features and its relevance in atherosclerosis Ferroptosis, a form of iron-dependent programmed cell death identified in 2012, is characterized by the accumulation of lipid hydroperoxides, ultimately leading to cellular damage and death ( The classical ferroptosis pathway is regulated by the Cystine/GSH/GPX4 axis

increased power performance and endurance volumes.

Experimental studies had shown a role of insulin in neuronal survival and synaptic maintenance and there is evidence for insulin resistance in PD brains [182]

Both approaches have merit, and the choice should be based on specific research objectives and the nature of the condition being studied