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The incidence of adrenal medullary hyperplasia and pheochromocytoma increased in male rats given 1 mg/kg/day (below clinical exposure at the maximum recommended human dose [MRHD] based on AUC) and in female rats at all dose levels (below clinical exposure at the MRHD based on AUC)

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Mitochondria Synthesize Melatonin to Ameliorate its Function and Improve Mice Oocytes Quality Under in Vitro Conditions