christian klow

christian klow Lowe (@CLoweWrites) • Facebook christian klow current stack: R

Name: christian klow Lowe (@CLoweWrites) • Facebook christian klow current stack: R
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In this article we first highlight and summarize recent insights on the role of ER stress and its associated signaling mechanisms on -cell function and diabetes and second how the ER stress pathways could be targeted in vitro during direct differentiation protocols for generation of hPSC-derived pancreatic -cells to faithfully phenocopy all features of bona fide human -cells for diabetes therapy or drug screening