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Overall, the molecular players involved in adipocyte lipolysis have multiple activities that are likely to be determined by subcellular location, availability of substrates and proximity to binding partners and coupled enzymes

doi:10.1111/j.1360-0443.2006.01699.x

Morphological changes in the adrenal glands following hypothyroidism effect were reported in several works

That difference compromises the integrity of peptide experiments because contaminated peptides can produce inflammatory artifacts, off-target effects, or simply degrade faster than expected