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Research has indicated that lactate that has accumulated within cancer cells is transported extracellularly by the monocarboxylate transporter MCT4, which not only facilitates the acceleration of glycolytic flux but also increases the acidity of the TME and promotes angiogenesis [71]

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Asked recently whether the molecule is even what the original team believed it was, one of Sikirics collaborators told Undark, As long as it works and has no side effects, who cares? If you read my work, you know Im not big for pathophysiology

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Cell 148 (3), 399408

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This could be used as a genetic background to globally switch ON/OFF a regulatory protein and establish a specific cellular reaction compartment or micro reactor

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