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Ashley SN, Somanathan S, Giles AR, Wilson JM

J Cardiovasc Pharmacol 1997

The detection of DNA methylation, which is an epigenetic modification responsible for many physiological and pathological processes in the human body, is very important for understanding the mechanisms of gene expression, as well as for adding complexity to traditional points-of-view

Notably, CCR7 is up-regulated in naive B cells through a Gpr174 and Gs-dependent mechanism, and Gpr174 may exert a synergistic effect with CCR7 during B cell activation [43]