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Vitamin D supplements are therefore not successful unless glutathione status is at optimal levels [12]

The results indicated the induction of oxidative stress, lung inflammation and injury, and cell proliferation due to nano-Co and showed the potential health effects of nanoparticle exposure (Wan et al., 2017)

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Thus, the malfunction of the hypothalamus or pituitary gland will be associated with low production of GnRH and gonadotropins, which in turn will lead to the gonadal failure, known as hypogonadotropic hypogonadism (23)