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Molecular dynamics simulations suggest novel allosteric modes in the Hsp70 chaperone protein

In this study, the authors generated recombinant adenoviruses expressing membrane-targeted modified green fluorescent protein (rAd-GFP) or ovalbumin (rAd-OVA) by infecting dendritic cells (DCs) with the viruses

Transgenic overexpression of Sry sensitizes mice to APAP-induced liver damage and apoptosis, whereas hepatocyte-specific knockout of Sry protects against these conditions We previously reported the generation of hepatocyte-specific Sry transgenic mice ( Sry- TG) overexpressing Sry in hepatocytes under the control of the albumin (Alb) gene promoter [17], as well as hepatocyte-specific Sry knockout mice ( Sry HC ) generated by crossbreeding SRY flox mice ( Sry fl/fl ) with Alb-Cre transgenic mice [18]

As with hypothyroidism, hyperthyroidism also has its dormant, subclinical form