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With increased excretion of CO due to increased workload, COHb levels become saturated

Frataxin deficiency in FA leads to changes in iron handling by the body as well as changes in metabolic pathways, the way chemicals are broken down in the body

Once you have chosen a site, use the alcohol pad to clean it

Because of the risk of toxicity, patients with TPMT or NUDT15 deficiency require alternative therapy or dose modification (see DOSAGE AND ADMINISTRATION)