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[5] Pregnancy: Sermorelin is categorized as Pregnancy Category C (under the older FDA classification system)

It can transactivate ferritin in response to ferroptosis triggers and inflammation, and by regulating p21, it can bolster the antioxidative defenses of the brain, particularly by inhibiting glutathione degradation and enhancing GPX4 activity [67]

The trial also met all key secondary endpoints, including improvements in waist circumference , systolic blood pressure, triglycerides, non-HDL cholesterol, LDL cholesterol, and serum uric acid