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Description

This technology involves genetic modification of parent cells, membrane modification, or in vitro modification of isolated vesicles to enhance their therapeutic efficacy or compensate for the limitations of natural EVs

I.SawantP

In contrast, in cancer cells, genetic mutations can lead to chronic hyperactivation of the mTOR pathway, fueling tumor growth and bypassing the standard regulatory inhibitory mechanisms

Kantarjian HM, Jabbour EJ, Garcia-Manero G, Kadia TM, DiNardo CD, Daver NG, Borthakur G , Jain N, Waukau JB, Kwari MI, Ravandi F, Anderson BD, Iizuka K, Jin C, Zhang C, Plunkett WK