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Neal, J.M., Bernards, C.M., Butterworth IV, J.F., Di Gregorio, G., Drasner, K., Hejtmanek, M.R., Mulroy, M.F., Rosenquist, R.W

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This pilot study suggest that the nasal drops may be used as an alternative to injections because two thirds of ME/CFS patients reported a positive effect, accompanied by an increased number of steps, improvement of the RAND-36 physical functioning scale and the CIS20r fatigue scale, and a significant increase in serum vitamin B12 levels