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congenital lingual melanotic macule

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Moreover, some of the brain-based interventions might also affect other regions of the brain or body, and perhaps systemically, or vice versa (e.g., if the delivered drug goes from the brain to the periphery, or indirect effects of a reduction in neuroinflammation reducing peripheral inflammation)

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When tumor volume reached about 50 mm 3 (volume=length x width 2 /2), mice were administered shRNA lentivirus (sh NC , negative control shRNA lentivirus

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This renders them predominantly effective in contexts where cancer cells have acquired resistance to cystine deprivation, such as through alternative amino acid transporters, upregulated transsulfuration pathways, or compensatory antioxidant networks (Du and Guo, 2022)

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There is a theoretical --- though as yet unproven in humans --- risk that long-term or high-dose use could stimulate growth in existing malignant or pre-malignant cells

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