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E2 is principally synthesized by ovaries, corpus luteum and placenta but it is also produced by other tissues such as the brain, adipose tissue, bone, vascular endothelium, and aortic smooth muscle cells [5]

published a series of SPS-based PROTACs targeting hematopoietic prostaglandin D synthase (H-PGDS) and BRD4 proteins resulting from the conjugation of different chemical procedures, such as amide coupling chemistry, click-chemistry, and urea formation

rednicka P, Juszczuk-Kubiak E, Wjcicki M et al (2021) Probiotics as a biological detoxification tool of food chemical contamination: a review