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2.8 DNA fragmentation assay The DPA assay is a colorimetric and quantitative technique used to evaluate DNA fragmentation in T-47D and resistant T-47D cells treated with BV, DOX, and BV + DOX

Rather than directly activating GABA-A receptors, the peptide appears to maintain homeostasis of the entire GABA receptor complex, preventing the desensitization and compensatory changes that produce tolerance and dependence

The peptide research section covers these mechanisms in greater detail for those wanting deeper scientific understanding

S4), indicating a potential substitution of Sec by Cys at this site during evolution