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Trends Biochem Sci 2021;46:329343

Supporting fibroblast activity may encourage tissue repair

It affects an enzyme called NNMT, which acts like a metabolic leakdraining away essential components: NAD (crucial for energy production) SAM (the universal methyl donor) This is significant, especially since NNMT is upregulated in conditions such as obesity, diabetes, Alzheimers, Parkinsons, and aging