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Description

When designing an amylin-analog it was important to address the aggregatory nature of this protein

Nevertheless, there is limited information about the behavior of MAPK/ERK1/2 pathway in steroidogenesis [53, 66]

Because it is unlikely that Glu would be modified by 4-OXO-DHA, our results support that 4-OXO-DHA (an electrophilic Michael acceptor) can covalently bind to the peptide containing the sequence of the active site of NF-B p50 protein to form a covalent linkage with the nucleophilic Cysteine-S 62 residue (marked in bold and italic in Table 1)