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Synthetic tetrapeptide Epitalon restores disturbed neuroendocrine regulation in senescent monkeys

They are studied in different ways, so a better answer is not a clean one

Tian, J., Goldstein, J

showed that, after stratifying the treated population by age, vitamin supplementation was associated with reduced risk of stroke and myocardial infarction in patients older than 69 [220], suggesting that older patients are more likely to benefit from this B vitamin therapy