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Thereafter, the AMP monomers will self-aggregate into the -helix polymer with their hydrophilic side constituting the barrel-like hollow channel and insert into the hydrophobic membrane cores more deeply, forming transient transmembrane pores which may disrupt the ion gradients and transmembrane potential and eventually lead to cell death

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Dysregulation of this axis underpins comorbidities such as heart failure-associated cognitive decline and Takotsubo cardiomyopathy, where emotional stress triggers acute cardiac dysfunction [80]

Obviously this ignorance can lead to serious consequences