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During COPD progression, during bacterial and viral infections, IL-17 and IL-22 have distinct clinical significance

Previous studies on global SUMOylation have focused on the dynamic nature of this modification playing roles during development, and associations between SUMOylation and neurodegeneration gaining traction however roles for SUMOylation in the central nervous system during the process of human aging remain understudied [111, 112]

doi: 10.1111/cge.12896

Current research supports the evidence that the gut microbiome (GM), which consists of gut microbiota and their biologically active metabolites, is associated with atherosclerosis development