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Mol Cancer Res (2021) 19(5):83446

Researchers also identified a new class of compounds, "PIPI drugs" (Psychedelic drug Informed but Psychedelic experience Inactive), that retain therapeutic benefits without evoking psychedelic experiences, opening entirely new frontiers for the treatment of mental health and inflammatory disease

Free Radic Biol Med (2017) 111:11026

But it explains why GHRP-6 results can vary significantly between individuals, because the health of the entire GH axis matters, not just the pituitary response