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The antioxidant property of Sp was however, found to be insensitive to depletion of glutathione by BSO, which generally causes loss of cellular antioxidant function and higher ROS (Fig

doi: 10.1016/j.cgh.2015.02.019 230 SugimotoKIkeyaKBambaSAndohAYamasakiHMitsuyamaKet al

Although this transfer of electrons down these pathways is known, many questions about the cytoplasmic redox pathways remain unanswered, such as their redundancy and specificity