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Similarly, external supplementation with NAC restores cysteine level, which decreased during hypobaric hypoxia, eliminates endogenous hydrogen sulfide concentrations, and reduces neuronal dysfunction (195)

Arsenic affects expression and processing of amyloid precursor protein (APP) in primary neuronal cells overexpressing the Swedish mutation of human APP

While the pathways are well elucidated and the fine details of their molecular mechanisms are beyond the scope of this manuscript, it is worth noting that not all patients suffer the same fate when it comes to APAP ingestion and hepatotoxicity