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Tirzepatide, a dual GLP-1 and GIP receptor agonist, works by reducing appetite and improving blood sugar controlbut some patients experience reduced nutrient absorption during active weight loss

According to the Lilly statement, this discovery is concerning because nothing is known about the short- or long-term effects of this molecule in humans, or whether there are any potential impacts on the drugs efficacy, toxicity, or immune reactions

For comparison, combining multiple appetite-modifying agents often creates unpredictable effects on hunger, energy intake, and metabolic rate

Adipose focus Studied specifically in fat-tissue metabolism