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Tanda-tanda gangguan ginjal, termasuk perubahan signifikan pada frekuensi buang air kecil atau pembengkakan pada kaki dan pergelangan kaki

Musial C, Kuban-Jankowska A, Gorska-Ponikowska M

Such encapsulation of metal ions in the protein interior might hinder their dissociation and exclude formation of ternary ligand exchange complexes leading to kinetical inertness of the CuCP complex at pH 7.4

The importance of anti-oxidant defense in psychosis onset has been emphasized in a recent systematic review, reporting decreased level of non-enzymatic antioxidants, increased level of lipid peroxides and nitric oxides, and a homeostatic imbalance of purine catabolism, while total decreased antioxidant capacity was significantly associated with cognitive deficits and negative symptoms [72]