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Curr Med Chem 2012

The dimeric form of GPI is a prerequisite for catalytic activity because the active site of the enzyme is composed of polypeptide chains from both subunits.50,145 The gene encoding GPI (GPI) is located on chromosome 19q13.1 and consists of 18 exons, spanning at least 50 kb, with a cDNA 1.9 kb in length

Sample preparation and microscope properties are potential stress sources and can thus influence glutathione redox state and distribution within the compartments

c , The PDK1-silenced HCT116 cells stably expressing PDK1 WT or K163R were serum-starved and treated with insulin for 0 or 30 min, followed by IF with anti-Akt (red), anti-SETDB1 (green) and DAPI (blue)