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Along these lines it is interesting that elevated expression of mammalian 14-3-3 can promote alpha synuclein extrusion 63 , akin to our finding that 14-3-3 protein FTT-2 is required for efficient exophergenesis and can drive enhanced exopher production when over-expressed in C

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During ones youth, most of the bodys requirement for carnitine is met by internal production of carnitine from lysine, as well as by dietary sources such as red meat and dairy products.1 An increasing body of evidence, however, indicates that to obtain enough carnitine to secure its protective effects against aging requires supplementation in addition to dietary sources.2 While scientific studies initially focused on the simplest form of carnitine, known as L-carnitine, recent findings suggest that specialized carnitine formulations may provide more dramatic, tissue-specific benefits.3 Acetyl-L-carnitine is the most widely studied carnitine supplement