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The rapidity of clinical decline and death in ALS has led many to investigate whether there could be an infectious etiology of the disease, primarily leading to research into transposable elements of the genome, meaning parts of genes that can jump from one chromosome to another and are present and essential in the healthy human genome [265]

insulin, glucagon-like peptide 1 (GLP-1) receptor agonists, sodium-glucose cotransporter 2 (SGLT2) inhibitors and sulphonylureas but NOT metformin or GLP-1 agonists [178] should be particularly cautious when considering the ketogenic diet

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