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It is not affected by peptidases in the blood, and is absorbed intact into the cell where the acetyl group is cleaved off producing an intact reduced glutathione

Alshuniaber et al

Users report mixed results when supplementing with alpha-lipoic acid, with some noting increased energy and feelings of general well-being and reduction in nerve pain, while others report an increase in fatigue and mental fogginess , to which some attribute to an alleged redistribution of mercury. One individual claimed to have removed heavy metals by taking 1 g/day of DMSA (in addition to N-Acetylcysteine and alpha-lipoic acid) for 3 days every 2 weeks, which eliminated chronic Candida infections and persistent anxiety and brain fog

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