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3 The 2013 American College of Cardiology (ACC)/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults stated that hs-CRP may be considered to guide treatment decision making if, after quantitative risk assessment, a risk-based treatment decision is uncertain

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Fourth, the study population was derived from a single geographic region (Northeast China) and recruited primarily from hospital settings, which constrains external validity and limits generalizability to broader or more diverse populations

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