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doi: 10.2903/j.efsa.2022.e200410

In addition to long-lived proteins, AGEs can bind to proteins with short half-lives such as serum albumin, thereby activating RAGEs and inducing inflammatory responses followed by protein dysfunction and cell damage 34

Developing combinational therapies that address neuronal hyperexcitability as well as oxidative stress may prevent the deleterious cycle of neuroinflammation and oxidative stress that contribute to epileptogenesis