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A systematic review of dexmedetomidine pharmacology in pediatric patients

Additionally, PFs can affect the gutliver axis through the activation of the FXR/RXRPXR signaling pathway, thereby increasing the capacity of the liver to detoxify foreign substances and increasing the ability of the liver to remove harmful toxins from the body via bile acids, thus illustrating the systemic detoxification effect initiated in the gut (Zhang et al