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Barr J, Horowitz M, Yonas H, Jungreis C, Horton J

Curcuminoids may interfere with the activity of efflux drug transporters of the ATP-binding cassette (ABC) family, including P-glycoprotein, multidrug resistance protein (MRP), and breast cancer-resistant protein (BCRP), which function as ATP-dependent efflux pumps that actively regulate the excretion of a number of drugs limiting their systemic bioavailability (116, 117)

10.1177/1933719115612133 22 HarrisM

These results indicate that the global transcriptomic profiles of the M and the C groups can be significantly distinguished, confirming that exogenous MT can disturb the global transcriptomic profile to enhance astaxanthin biosynthesis in P