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Musunuru K, Chadwick AC, Mizoguchi T, Garcia SP, DeNizio JE, Reiss CW, et al

Oxidative stress and cardiovascular risk in type 1 diabetes mellitus: insights from the DCCT/EDIC study

Overall, our results demonstrate that, energy restriction with fasting traditional once-per-day CR was highly effective in improving cognition, reducing not only A plaques but also hyperphosphorylation of tau and tau pathology, reducing neuroinflammation, and was accompanied by molecular changes believed to be beneficial, notably the reduction of mTORC1 signaling and activation of autophagy