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Lyophilized Melanotan-2 stored at 20C remains stable for years, but any temperature excursion above 8C after reconstitution causes irreversible structural damage that neither appearance nor home testing can detect

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Clinically important information includes: stage of the disease (ie active versus chronic) curvature features (ie direction, degree) penile length and other associated penile deformities (eg hourglass deformity) presence of pre-existing or co-existing erectile dysfunction

This condition predominantly affects the gingiva, hard palate, and buccal mucosa, with the severity of pigmentation directly proportional to the cumulative exposure to tobacco