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186 Additionally, the activation of the transcription factor FOXA1 has been observed in EGFR mutant NSCLC treated with Osimertinib, resulting in the upregulated expression of IGF-1R and induction of the DTP cells

8,9 More than 130 articles from MEDLINE related to oxidative stress and antioxidants during 19902014 revealed that the imbalance between the formation of oxidants and the availability of endogenous antioxidants are the major determinant of endometriosis

KEAP1, which promotes the ubiquitination and subsequent degradation of NRF2, a key regulator of the antioxidant response, was upregulated in chemotherapy-sensitive tumors, suggesting that targeting the NRF2KEAP1 pathway could enhance the sensitivity of MIBC cells to cisplatin

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