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infusions, an exceptionally large amount of CrEL is necessary, resulting in important biological events that can lead to serious acute hypersensitivity reactions and neurological toxicity

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Yang W, Chen YH, Liu H, Qu HD (2015) Neuroprotective effects of piperine on the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsons disease mouse model