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I absolutely have to do exercise just like I have to brush my teeth. Rhonda Patrick She works out about 5 to 6 hours a week total broken down like this: Two sessions a week that are CrossFit style, one hour each, first 30 minutes is heavy strength training, last 30 minutes is HIIT (rowing machine, assault bike, lighter cleans with more reps) Two more sessions a week with her girlfriends, about an hour and 20 each, same style but more social and more recovery time between sets Running about 4 to 6 miles a week total, sometimes with her husband, which she genuinely enjoys Weekend hikes with the family, sometimes with a sprint up a hill, but mostly just moving in nature Even just 10 minutes of vigorous exercise immediately increases neuronal connections in the brain The data for this is insane 9 minutes a day of vigorous bursts (3 minutes, 3 times) links to a 40% reduction in all-cause mortality, 40% reduction in cancer mortality, and 50% reduction in cardiovascular mortality The biggest unexpected benefit of heavy strength training was not physical I would say the biggest effect was on my brain and the ability to handle stress better

Nat Chem Biol 13 , 486493 (2017)

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Calcium Channel Blocker Verapamil (VP) is a calcium channel blocker used for hypertension treatment that also acts as an inhibitor of drug efflux protein