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We thank Shuyun Tian for the assistance in the early stage of the project

232,233 In addition to pathways involved in iron metabolism, several other molecular pathways have also been implicated in ferroptosis, including the guanosine triphosphate cyclohydrolase 1/tetrahydrobiopterin (GCH1/BH4) axis, 234 the cysteine/glutathione/glutathione peroxidase 4 (GSH/GPX4) axis, 235,236 and the ferroptosis suppressor protein 1/coenzyme Q (FSP1/CoQ) axis

These layers facilitate the mixing of nutrients through convection currents, where warmer, less dense water rises, while colder, denser water sinks

This is why vegetarians and vegans , in particular, need to ensure they are getting adequate iron from their more limited diet