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To understand the catalytic mechanism of the ADP-ribosylhydrolase (ARH) activity of MavL, we screened its active truncation mutants and succeeded in solving the structure of the MavL 40-404 -ADPR complex at a resolution of 2.38 , which revealed that several pairs of hydrogen bonds and a - stacking interaction provided by surrounding amino acids or water molecules are involved in interactions between MavL and ADPR (Supplementary Fig

Sodium thiosulfate, a source of hydrogen sulfide, stimulates endothelial cell proliferation and neovascularization

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This study also revealed lower levels of glutathione in the anterior cingulate cortex (ACC) and thalamus, which supports the idea of origin of glutamate from glutathione (16)