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classified as a compounded drug with active import alerts Human trial evidence / Zero completed Phase II or III RCTs in any condition as of 2025 Tumor-promotion signal / Rat models show accelerated solid-tumor growth at supraphysiologic doses Cardiovascular concern / Dual vasomotor activity reported: hypotension at low doses, hypertension at high doses in rodents Hormonal interference / Modulates dopamine and serotonin pathways

doi: 10.3389/fendo.2023.1109747 319

The productivity adjustment is set forth in section 1833(i)(2)(D)(v) of the Act