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The close interplay of nitro-oxidative stress, advanced glycation end products and inflammation in inflammatory bowel diseases

[PMC free article: PMC4526153] [PubMed: 24220094] 544

This leads to strong induction and stabilization of CYP2E1 in the liver and other tissues

these variants seem to be inherited through recessive inheritance in the case of PFIC, while less severe diseases like ICP or LPAC are likely to be inherited as autosomal dominant variations