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Description

Methods Animals All animals were kept on a mixed genetic background (C57BL/6J;129)

5m, n), which is consistent with previous observations that SIRT7 prevented AKT K63-linked ubiquitination (Fig

(Haematologica) XIth International Myeloma Workshop & IVth International Workshop on Waldenstrms Macroglobulinemia 92(6):172, (abstr PO-662), 2007

PLP interacts with the carboxylate of Asp 187 of CSE via hydrogen bonding and mutation of this residue to Ala abolishes catalytic activity, as assessed by H 2 S production